P-Cresol

P-Cresol

SCHEMBL8464882

Cc1ccc(O)cc1.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of P-Cresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.65
LMNA P02545 3/20 0.46
TSHR P16473 1/20 0.46
ALDH1A1 P00352 4/20 0.44
GAA P10253 3/20 0.44
HPGD P15428 3/20 0.42
ESR2 Q92731 1/20 0.42
ESR1 P03372 1/20 0.41
MAPT P10636 5/20 0.41
RAB9A P51151 3/20 0.41
POLB P06746 2/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
ENPP2 Q13822 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
ALOX15 P16050 2/20 0.41
BLM P54132 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cresol SCHEMBL9785887 1.00 ACHE (0.65) ACHELMNATSHRALDH1A1GAA
P-Cresol SCHEMBL10686122 0.95 ACHE (0.65) ACHELMNATSHRALDH1A1GAA
P-Cresol SCHEMBL11677207 0.95 ACHE (0.65) ACHELMNATSHRALDH1A1GAA
P-Cresol SCHEMBL9455034 0.93 ACHE (0.62) ACHELMNATSHRALDH1A1GAA
Hydroquinone SCHEMBL30361056 0.87 CA1 (0.53) ACHELMNAALDH1A1HPGDESR2
P-Xylene SCHEMBL10690560 0.87 ACHE (0.53) ACHELMNATSHRALDH1A1GAA
P-Cresol SCHEMBL30339010 0.84 ACHE (0.72) ACHELMNATSHRALDH1A1GAA
P-Cresol SCHEMBL30644866 0.84 ACHE (0.72) ACHELMNATSHRALDH1A1GAA
P-Cresol SCHEMBL28453798 0.84 ACHE (0.72) ACHELMNATSHRALDH1A1GAA
P-Xylene SCHEMBL28237278 0.84 LMNA (0.52) ACHELMNATSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076367-A1 ENDOSCOPE DISINFECTANT WHITELEY CORP PTY LTD (AU) 2026-03-19 US claimed
US-12427215-B2 Endoscope disinfectant WHITELEY CORPORATION PTY LTD (AU) 2025-09-30 US claimed
US-20220023475-A1 IMPROVED ENDOSCOPE DISINFECTANT WHITELEY CORPORATION PTY LTD (AU) 2022-01-27 US claimed
EP-3923721-A1 IMPROVED ENDOSCOPE DISINFECTANT Whiteley Corporation Pty Ltd (AU) 2021-12-22 EP claimed
WO-2020163900-A1 IMPROVED ENDOSCOPE DISINFECTANT WHITELEY CORPORATION PTY LTD (AU) 2020-08-20 WO claimed
US-5936048-A Method for preparing modified resins and their applications MITSUI CHEMICALS, INC. (JP) 1999-08-10 US disclosed
US-5869184-A RESIN RAW MATERIALS FOR PAINTS, ADHESIVES MITSUI TOATSU CHEMICALS, INC. (JP) 1999-02-09 US disclosed
EP-0698620-B1 Method for preparing modified resins and their applications MITSUI CHEMICALS INC (JP) 1998-12-09 EP disclosed
US-5792814-A REACTING A RESIN WITH A 5-((4,6-DIAMINO-S-TRIAZIN-2-YL)-NORBORN-2-ENE AND REACTING WITH AN EPOXIDE; FIREPROOFING; MOLDING MATERIALS MITSUI CHEMICALS, INC. (JP) 1998-08-11 US disclosed
US-5744504-A AMINO RESIN; THERMOSETTING MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-28 US disclosed
US-5674947-A HEATING RESIN WITH FUNCTIONALIZED NORBORNENE COMPOUND IN ABSENCE OF REACTION CATALYST OR INITIATOR MITSUI TOATSU CHEMICALS, INC. (JP) 1997-10-07 US disclosed
US-5648446-A ADHESIVES, FIREPROOFING, HEAT RESISTANCE IN RESINS FOR MOLDING MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
US-5596039-A FLAME RETARDERS, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-01-21 US disclosed
US-5569726-A USEFUL IN FLAME-RETARDING, THERMAL STABILIZATION AND COMPATIBILIZATION OF RESINS AND IN THERMOSETTING MOLDING COMPOSITIONS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-10-29 US disclosed
US-5545702-A THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-13 US disclosed
US-5536795-A ADHESIVES AND PAINTS AND FIREPROOFING THERMOSETTING RESINS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-16 US disclosed
EP-0698620-A1 Method for preparing modified resins and their applications MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-02-28 EP disclosed
US-5480947-A N-METHYLOL DIGUANAMINES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0612797-A2 Modification method of resins MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-08-31 EP disclosed
US-4218329-A AQUEOUS SOLUTION OF MOLYBDATE, REACTION PRODUCT OF AROMATIC SULFONAMIDOCARBOXYLIC ACID AND AMINE, METAL DEACTIVATOR, AND COUPLER KOH KOOK WHA 1980-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260076367-A1 ENDOSCOPE DISINFECTANT PMS2, GABBR1, GABRP ACHE 4124/4885LMNA 4106/4885TSHR 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.