Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005383 | 0.95 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL13609815 | 0.86 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2MAPTTHRB | |
| SCHEMBL11299833 | 0.83 | MEN1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8467758 | 0.83 | LMNA (0.64) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9571811 | 0.82 | MTNR1A (0.71) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6396790 | 0.82 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL439393 | 0.82 | RXFP1 (0.74) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9095411 | 0.81 | KMT2A (0.63) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL166821 | 0.81 | MAPT (0.67) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8465247 | 0.81 | RXFP1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936038-A | MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE | THE UNIVERSITY OF AKRON (US) | 1999-08-10 | — | — | US | claimed |
| US-5936038-A | MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE | THE UNIVERSITY OF AKRON (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0570825-B1 | Tire sidewall composition containing silica having low PH | GOODYEAR TIRE & RUBBER (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0475215-B1 | Carboxylic acid esters with thio groups | GOODYEAR TIRE & RUBBER (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0570825-A1 | Tire sidewall composition containing silica having low PH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5244028-A | Natural rubber or polybutadiene, silica, antidegradation agent, carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5216049-A | A phenolic or amine stabilizer and an organothioalkylene styrene bound to a polymer; aging resistance; rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0475215-A1 | Carboxylic acid esters with thio groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5069819-A | SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-03 | — | — | US | disclosed |
| US-4281080-A | TACKIFIERS FOR RUBBERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4010140-A | Age resistant resin compositions and admixtures useful as adhesives | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-03-01 | — | — | US | disclosed |