Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825578 | 0.79 | HPGD (0.33) | ALDH1A1HPGDTDP1TSHRMAPK1 | |
| SCHEMBL1255978 | 0.72 | TDP1 (0.37) | ALDH1A1HPGDTDP1TSHRCYP3A4 | |
| SCHEMBL2156705 | 0.66 | — | — | |
| SCHEMBL3886650 | 0.62 | TSHR (0.42) | ALDH1A1HPGDTDP1TSHRCYP3A4 | |
| SCHEMBL4621245 | 0.61 | TDP1 (0.58) | ALDH1A1HPGDTDP1TSHRCYP3A4 | |
| SCHEMBL9187681 | 0.59 | THRB (0.44) | ALDH1A1CYP3A4MAPK1HIF1AMAPT | |
| SCHEMBL1345309 | 0.58 | TSHR (0.48) | ALDH1A1HPGDTDP1TSHRCYP3A4 | |
| SCHEMBL1185274 | 0.58 | GAA (0.36) | ALDH1A1HPGDTDP1TSHRHSD17B10 | |
| SCHEMBL7697555 | 0.58 | TAAR1 (0.34) | ALDH1A1TDP1TSHRCYP3A4ALOX15 | |
| SCHEMBL182877 | 0.58 | MAPT (0.52) | ALDH1A1HPGDTDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676403-B1 | Arylaminosilane end-capped urethane sealants | WITCO CORP (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0676403-A1 | Arylaminosilane end-capped urethane sealants | OSI SPECIALTIES, INC. (US) | 1995-10-11 | — | — | EP | claimed |
| EP-0676403-B1 | Arylaminosilane end-capped urethane sealants | WITCO CORP (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0676403-A1 | Arylaminosilane end-capped urethane sealants | OSI SPECIALTIES, INC. (US) | 1995-10-11 | — | — | EP | disclosed |