SCHEMBL846746

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL846747	1.00	P4HA1 (0.53)	P4HA1P4HTMMIFHCAR3GABRP
	SCHEMBL846330	0.80	MAPK1 (0.59)	ALDH1A1MAPT
	SCHEMBL846331	0.80	MAPK1 (0.59)	ALDH1A1MAPT
	SCHEMBL1441457	0.80	P4HA1 (0.57)	P4HA1P4HTMMIFHCAR3GABRP
	SCHEMBL9000735	0.79	P4HA1 (0.52)	P4HA1P4HTMMIFHCAR3GABRP
	SCHEMBL845436	0.78	P4HA1 (0.55)	P4HA1P4HTMMIFHCAR3GABRP
	SCHEMBL11472332	0.78	MEN1 (0.52)	P4HA1P4HTMMIFHCAR3GABRP
	SCHEMBL11472328	0.78	MEN1 (0.52)	P4HA1P4HTMMIFHCAR3GABRP
	SCHEMBL16935142	0.76	MLYCD (0.43)	ALDH1A1CYP1A2HPGDCYP2C19
	SCHEMBL16935143	0.76	MLYCD (0.43)	ALDH1A1CYP1A2HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.