SCHEMBL846917

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL846066	0.84	CNR2 (0.41)	POLBALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL21026592	0.81	CA12 (0.47)	POLBALDH1A1PPARARXRA
	SCHEMBL4257732	0.77	POLB (0.50)	LTB4RLTB4R2POLBALDH1A1KDM4E
	SCHEMBL491024	0.77	POLB (0.50)	POLBALDH1A1KDM4EFFAR1HPGD
	SCHEMBL29140671	0.77	ALDH1A1 (0.46)	POLBALDH1A1KDM4ELMNAFFAR1
	SCHEMBL145533	0.74	TSHR (0.50)	LTB4RLTB4R2POLBALDH1A1KDM4E
	SCHEMBL146097	0.73	ALDH1A1 (0.47)	LTB4RLTB4R2POLBALDH1A1FFAR1
	SCHEMBL7794917	0.72	FFAR1 (0.48)	PPARAFFAR1FFAR4FFAR2PPARD
	SCHEMBL12121971	0.71	PTGS2 (0.52)	ALDH1A1KDM4EMAPT
	SCHEMBL28797366	0.71	POLB (0.41)	LTB4RLTB4R2POLBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.