SCHEMBL846974

SCHEMBL846974

CC1(C(=O)O)COC(=O)OC1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.46
MAPK1 P28482 3/20 0.41
LMNA P02545 2/20 0.32
TP53 P04637 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
STAT6 P42226 1/20 0.32
HIF1A Q16665 1/20 0.32
NPC1 O15118 1/20 0.32
GMNN O75496 1/20 0.32
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846811 0.81 LMNA (0.30) LMNACYP2C9
SCHEMBL847157 0.79 NR1I2 (0.31)
SCHEMBL12634644 0.79 PKM (0.33)
SCHEMBL847017 0.76 DRD2 (0.33)
SCHEMBL663921 0.76 MEN1 (0.33) NPC1RAB9ASMN1; SMN2NPSR1
SCHEMBL847067 0.76 ALDH1A1 (0.36) SMN1; SMN2
SCHEMBL12688265 0.74
SCHEMBL19500000 0.74 FFAR3 (0.44) FFAR3MAPK1LMNATP53CYP2C9
SCHEMBL17688059 0.74 ATM (0.31)
SCHEMBL353254 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939927-A SuFEx click reaction-based cyclic carbonate monomer, polymer and preparation method thereof 苏州大学 2021-06-11 CN claimed
CN-109004280-B Preparation method of all-solid-state polymer electrolyte and all-solid-state polymer battery 珠海冠宇电池股份有限公司 2021-06-08 CN claimed
CN-109232929-B Preparation method of gel polymer electrolyte and lithium ion battery 珠海冠宇电池股份有限公司 2021-04-27 CN claimed
EP-2262845-A1 MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS University of Southern Mississippi (US) 2010-12-22 EP claimed
WO-2009102795-A1 MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2009-08-20 WO claimed
US-20090208553-A1 Monomers and Polymers with Covalently - Attached Active Ingredients UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2009-08-20 US claimed
US-12133895-B2 Biodegradable functional polycarbonate nanoparticle carries for delivering molecular cargo INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2024-11-05 US disclosed
US-12128063-B2 Biocompatible and biodegradable antiviral polymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2024-10-29 US disclosed
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-20230122378-A1 BIOCOMPATIBLE AND BIODEGRADABLE ANTIVIRAL POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-04-20 US disclosed
US-20230122378-A1 BIOCOMPATIBLE AND BIODEGRADABLE ANTIVIRAL POLYMERS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-04-20 US disclosed
US-20220111115-A1 A BONE CEMENT COMPOSITION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-04-14 US disclosed
EP-1904553-A1 METHOD OF BIOMOLECULE IMMOBILIZATION ON POLYMERS USING CLICK-TYPE CHEMISTRY Shoichet, Molly S. (CA) 2008-04-02 EP disclosed
EP-1807113-A2 SUSTAINED RELEASE OF ACTIVE MOLECULES FROM POLYMERS TOPICALLY APPLIED TO SKIN OR HAIR ELC Management LLC (US) 2007-07-18 EP disclosed
WO-2007003054-A1 METHOD OF BIOMOLECULE IMMOBILIZATION ON POLYMERS USING CLICK-TYPE CHEMISTRY SHOICHET MOLLY S (CA) 2007-01-11 WO disclosed
WO-2006047714-A2 SUSTAINED RELEASE OF ACTIVE MOLECULES FROM POLYMERS TOPICALLY APPLIED TO SKIN OR HAIR ELC MANAGEMENT LLC (US) 2006-05-04 WO disclosed
US-20060088489-A1 Sustained release of active molecules from polymers topically applied to skin or hair POLYTECHNIC UNIVERSITY 2006-04-27 US disclosed
US-6972315-B2 Enzyme-catalyzed polycondensations SyntheZyme, LLC 2005-12-06 US disclosed
US-20040019178-A1 Enzyme-catalyzed polycondensations SyntheZyme, LLC 2004-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12133895-B2 Biodegradable functional polycarbonate nanoparticle carries for delivering molecular cargo ABCB11, ABCB1, PCBP1 FFAR3 3787/4885MAPK1 2824/4885LMNA 1105/4885
US-20230122378-A1 BIOCOMPATIBLE AND BIODEGRADABLE ANTIVIRAL POLYMERS CD44, PUF60, SARS1 FFAR3 2226/4885MAPK1 2292/4885LMNA 3066/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS FFAR3 2534/4885MAPK1 3441/4885LMNA 4337/4885
US-12128063-B2 Biocompatible and biodegradable antiviral polymers CD44, PUF60, SARS1 FFAR3 2226/4885MAPK1 2292/4885LMNA 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.