SCHEMBL846811

SCHEMBL846811

CC(=O)C1(C)COC(=O)OC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846974 0.81 FFAR3 (0.46) LMNACYP2C9
SCHEMBL12634644 0.79 PKM (0.33)
SCHEMBL847157 0.79 NR1I2 (0.31)
SCHEMBL12688265 0.79
SCHEMBL847017 0.76 DRD2 (0.33)
SCHEMBL663921 0.76 MEN1 (0.33)
SCHEMBL17688059 0.74 ATM (0.31)
SCHEMBL1970312 0.74 KCNA4 (0.39)
SCHEMBL7996386 0.74
SCHEMBL19860154 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9987369-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-05 US disclosed
US-20180117162-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-05-03 US disclosed
US-20170202217-A1 ANTIBACTERIAL POLYMER, PRODUCTION METHOD THEREFOR, AND USAGE THEREOF NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) 2017-07-20 US disclosed
US-20170158811-A1 CYCLIC CARBONATE MONOMERS AND RING OPENED POLYCARBONATES THEREFROM INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-06-08 US disclosed
US-9637592-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-05-02 US disclosed
US-20170114183-A1 METHODS OF FORMING BLOCK POLYMERS FOR DIRECTED SELF-ASSEMBLY INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-04-27 US disclosed
US-20170051105-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-02-23 US disclosed
US-9562127-B2 Methods of forming block polymers for directed self-assembly INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-02-07 US disclosed
US-9511146-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-12-06 US disclosed
US-9388275-B2 Method of ring-opening polymerization, and related compositions and articles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-07-12 US disclosed
US-20110182996-A1 SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 US disclosed
US-20110182996-A1 SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 US disclosed
US-20110054064-A1 Hydrogel Compositions and Methods of Preparation Thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-03-03 US disclosed
US-20110009571-A1 SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS ALCON RESEARCH, LLC 2011-01-13 US disclosed
US-20100317838-A1 CYCLIC CARBONYL MONOMERS FUNCTIONALIZED WITH CARBOHYDRATES, POLYMERS DERIVED THEREFROM, AND METHODS OF PREPARATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-16 US disclosed
US-20100311917-A1 METHODS FOR MAKING MULTI-BRANCHED POLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2010-12-09 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305300-A1 Method of Ring-Opening Polymerization, and Related Compositions and Articles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-6228979-B1 REACTING PRIMARY AMINE OR ALKYLENIMINE WITH AN ALKYLENE CARBONATE BEARING A PENDANT KETONE OR ESTER MOIETY WITH QUICK REACTION TIMES TO YIELD CORRESPONDING DECYCLIZED HYDROXYALKYLCARBAMATE COMPOUND USEFUL AS REACTIVE DILUENT E. I. DU PONT DE NEMOURS AND COMPANY 2001-05-08 US disclosed
US-6020499-A Cyclic carbonates and their reactions with amines E. I. DU PONT NEMOURS AND COMPANY (US) 2000-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170202217-A1 ANTIBACTERIAL POLYMER, PRODUCTION METHOD THEREFOR, AND USAGE THEREOF WASF2, HASPIN, MRPL21 LMNA 2751/4885CYP2C9 2548/4885
US-20170051105-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS VDR, PROC, CYP24A1 LMNA 2391/4885CYP2C9 463/4885
US-20110182996-A1 SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY ABCB7, CD63, ITGB3 LMNA 1076/4885CYP2C9 1127/4885
US-20100317838-A1 CYCLIC CARBONYL MONOMERS FUNCTIONALIZED WITH CARBOHYDRATES, POLYMERS DERIVED THEREFROM, AND METHODS OF PREPARATION THEREOF FUT6, FUT5, WASF2 LMNA 1176/4885CYP2C9 3517/4885
US-20180117162-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS VDR, PROC, CYP24A1 LMNA 2122/4885CYP2C9 796/4885
US-20170158811-A1 CYCLIC CARBONATE MONOMERS AND RING OPENED POLYCARBONATES THEREFROM ACMSD, CARM1, PBRM1 LMNA 892/4885CYP2C9 2140/4885
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA LMNA 1875/4885CYP2C9 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.