Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563426 | 0.75 | CRBN (0.71) | CRBNALDH1A1KDM4E | |
| SCHEMBL6411615 | 0.69 | CRBN (0.46) | CRBNALDH1A1PDE3BPDE3AKDM4E | |
| SCHEMBL11552686 | 0.69 | PRKCH (0.44) | ALDH1A1KDM4EP2RX7KCNH2 | |
| SCHEMBL8474128 | 0.68 | CRBN (0.43) | CRBNALDH1A1PDE3BPDE3AKDM4E | |
| SCHEMBL5767440 | 0.68 | PIM1 (0.44) | OPRM1OPRL1P4HTMMAOBKDM4E | |
| SCHEMBL30638525 | 0.68 | GRM5 (0.55) | OPRM1OPRL1CCNA2CDK2 | |
| SCHEMBL30638528 | 0.68 | OPRM1 (0.41) | OPRM1OPRL1MAOBKDM4ECCNA2 | |
| SCHEMBL20390820 | 0.68 | GAA (0.43) | ALDH1A1MAOBKDM4EHTR1A | |
| SCHEMBL30638502 | 0.68 | GAA (0.43) | ALDH1A1MAOBKDM4EHTR1A | |
| SCHEMBL1713643 | 0.68 | MAOB (0.38) | OPRM1OPRL1ALDH1A1P4HTMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299360-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD (CN) | 2024-09-12 | — | — | US | disclosed |
| US-6004963-A | TUMOR NECROSIS FACTOR RELEASE INHIBITORS; IMMUNOMODULATORS | GRUENENTHAL GMBH (DE) | 1999-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299360-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | ADAMTS5, ADAMTS4, ADAMTS1 | CRBN 1432/4885OPRM1 4863/4885OPRL1 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.