Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470105 | 0.95 | ALDH1A1 (0.43) | ALDH1A1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL8079548 | 0.90 | ALDH1A1 (0.38) | ALDH1A1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL8469668 | 0.87 | ALDH1A1 (0.37) | ALDH1A1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL8469910 | 0.87 | LMNA (0.38) | ALDH1A1GAAMAPTHSP90AA1KEAP1 | |
| Bromide SCHEMBL8469213 | 0.85 | HSP90AA1 (0.48) | ALDH1A1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL8471272 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL8074300 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL8469817 | 0.84 | KEAP1 (0.40) | ALDH1A1KMT2AMAPTHPGDKEAP1 | |
| SCHEMBL8469903 | 0.82 | LMNA (0.40) | ALDH1A1GAAMAPTHSP90AA1HPGD | |
| SCHEMBL8469537 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KMT2AGAAMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |