Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 8/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066342 | 0.90 | ALDH1A1 (0.38) | KEAP1PIK3CGALDH1A1NFE2L2POLB | |
| SCHEMBL8470105 | 0.89 | ALDH1A1 (0.43) | KEAP1PIK3CGALDH1A1NFE2L2POLB | |
| SCHEMBL8469157 | 0.87 | KEAP1 (0.36) | KEAP1PIK3CGALDH1A1NFE2L2L3MBTL1 | |
| Bromide SCHEMBL8469666 | 0.86 | KEAP1 (0.48) | KEAP1ALDH1A1NFE2L2L3MBTL1LMNA | |
| SCHEMBL8470816 | 0.86 | KEAP1 (0.42) | KEAP1PIK3CGNFE2L2L3MBTL1CA12 | |
| SCHEMBL8470438 | 0.84 | ALDH1A1 (0.42) | KEAP1ALDH1A1NFE2L2POLBMAPT | |
| SCHEMBL8469910 | 0.82 | LMNA (0.38) | KEAP1ALDH1A1NFE2L2MAPTCA12 | |
| SCHEMBL8074300 | 0.80 | ALDH1A1 (0.40) | KEAP1PIK3CGALDH1A1NFE2L2MAPT | |
| SCHEMBL8471427 | 0.79 | ALDH1A1 (0.42) | KEAP1ALDH1A1NFE2L2L3MBTL1POLB | |
| SCHEMBL8469537 | 0.76 | ALDH1A1 (0.39) | KEAP1ALDH1A1NFE2L2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |