Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614890 | 1.00 | KMT2A (0.37) | KMT2ANPC1RAB9AGAAPPARG | |
| SCHEMBL8474347 | 0.93 | RAB9A (0.41) | KMT2ANPC1RAB9AGAAPPARG | |
| SCHEMBL7614886 | 0.93 | RAB9A (0.41) | KMT2ANPC1RAB9AGAAPPARG | |
| Hydrochloric Acid SCHEMBL8472257 | 0.89 | KDM4E (0.42) | KMT2ANPC1RAB9AGAAPPARG | |
| SCHEMBL7615055 | 0.88 | KDM4E (0.36) | KMT2AKDM4EMEN1ALDH1A1HTT | |
| SCHEMBL7615359 | 0.86 | DNM1 (0.36) | KMT2AKDM4EMEN1ALDH1A1HSD17B10 | |
| SCHEMBL8473304 | 0.85 | KDM4E (0.46) | KMT2ANPC1RAB9AGAAPPARG | |
| SCHEMBL8475760 | 0.85 | KDM4E (0.46) | KMT2ANPC1RAB9AGAAPPARG | |
| SCHEMBL8472046 | 0.85 | SLC6A5 (0.43) | KMT2AKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8474427 | 0.84 | KDM4E (0.46) | KMT2ANPC1RAB9AGAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |