Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615354 | 0.93 | DNM1 (0.41) | DNM1MEN1KMT2AEGFRSRC | |
| SCHEMBL7615055 | 0.89 | KDM4E (0.36) | MEN1KMT2APOLBPTGER4HTR6 | |
| Hydrochloric Acid SCHEMBL8473318 | 0.88 | MEN1 (0.38) | DNM1MEN1KMT2APOLBEGFR | |
| SCHEMBL8474836 | 0.86 | ENPP1 (0.37) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7614890 | 0.86 | KMT2A (0.37) | MEN1KMT2APOLBPTGER4KDM4E | |
| SCHEMBL8474349 | 0.86 | KMT2A (0.37) | MEN1KMT2APOLBPTGER4KDM4E | |
| SCHEMBL7618604 | 0.86 | HTR6 (0.35) | KMT2ASRCPTGER4HTR6HIF1A | |
| SCHEMBL8476267 | 0.85 | EGFR (0.46) | DNM1EGFRSRCPTGER4KDM4E | |
| SCHEMBL8477309 | 0.84 | EGFR (0.42) | DNM1MEN1KMT2APOLBEGFR | |
| SCHEMBL8472561 | 0.84 | HDAC3 (0.41) | KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |