SCHEMBL84789

SCHEMBL84789

O=CC1CN(C(c2ccccc2)c2ccccc2)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
OPRM1 P35372 3/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
ADRA2A P08913 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
DRD1 P21728 1/20 0.44
ADRA1D P25100 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HRH1 P35367 1/20 0.44
DRD3 P35462 1/20 0.44
HTR2B P41595 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14321910 0.98 KMT2A (0.43) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL27484546 0.77 ACHE (0.45) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL85389 0.77 SLC6A9 (0.42) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL16759363 0.74 SLC6A9 (0.46) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL6510613 0.74 OPRD1 (0.41) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL6510618 0.74 OPRD1 (0.41) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL48800 0.74 OPRM1 (0.48) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL72466 0.74 OPRM1 (0.48) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL5695024 0.74 OPRM1 (0.48) KMT2AOPRM1CHRM2CHRM4CHRM5
SCHEMBL6843039 0.74 OPRM1 (0.53) KMT2AOPRM1CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111117136-B Cable material 温州大学 2022-06-07 CN claimed
CN-111117136-A Cable material 温州大学 2020-05-08 CN claimed
CN-103517907-B Volution isoxazolines derivative as antiparasitic 硕腾服务有限责任公司 2016-07-06 CN claimed
CN-103517907-A Spirocyclic isoxazoline derivatives as antiparasitic agents PFIZER 2014-01-15 CN claimed
EP-4539849-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 Therapeutics, Inc. (US) 2025-04-23 EP disclosed
US-20250121070-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 THERAPEUTICS, INC. (US) 2025-04-17 US disclosed
US-11932633-B2 KRas G12C inhibitors Mirati Therapeutics, Inc. (US) 2024-03-19 US disclosed
WO-2023244764-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
WO-2023244764-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 C4 THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
CN-115650893-A Synthesis method of 1-benzhydrylazetidin-3-one 南通华祥医药科技有限公司 2023-01-31 CN disclosed
CN-115650893-A Synthesis method of 1-benzhydrylazetidin-3-one 南通华祥医药科技有限公司 2023-01-31 CN disclosed
CN-111117136-B Cable material 温州大学 2022-06-07 CN disclosed
CN-1185213-C Azetidine derivatives, preparation thereof and pharmaceutical compositions AVENTIS PHARMA SA (FR) 2005-01-19 CN disclosed
US-20040132714-A1 Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans WYETH 2004-07-08 US disclosed
CN-1149191-C Azetidine derivatives, Preparation and medicines containing them ���ĵ�˹ҩ��ɷ����޹�˾ 2004-05-12 CN disclosed
WO-2004024730-A1 ANTIDEPRESSANT AZAHETEROCYCLYLMETHYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS WYETH (US) 2004-03-25 WO disclosed
CN-1423633-A Azetidine derivatives, process for their preparation and pharmaceutical compositions containing them AVENTIS PHARMA SA (FR) 2003-06-11 CN disclosed
CN-1316991-A Azetidine derivatives, preparation and medicines containing them AVENTIS PHARMA SA (FR) 2001-10-10 CN disclosed
US-4200628-A ANTIBIOTICS, BACTERICIDES SHIONOGI & CO., LTD. (JP) 1980-04-29 US disclosed
EP-0001643-A2 Aminoglycoside derivatives, process for their manufacture, pharmaceutical compositions and carboxylic acids SHIONOGI & CO., LTD. (JP) 1979-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250121070-A1 COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 SMARCA2, SMARCE1, SMARCA1 KMT2A 612/4885OPRM1 4387/4885CHRM2 2735/4885
US-20040132714-A1 Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans CYP19A1, CRH, CYP17A1 KMT2A 3722/4885OPRM1 43/4885CHRM2 3412/4885
US-11932633-B2 KRas G12C inhibitors KRAS, NRAS, HRAS KMT2A 2081/4885OPRM1 4750/4885CHRM2 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.