SCHEMBL8480291

SCHEMBL8480291

Cc1nc(Cl)sc1CC=O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4435329 0.79 SLC6A3 (0.39) ALDH1A1
SCHEMBL289402 0.78 CYP1A2 (0.31)
SCHEMBL13802271 0.76
SCHEMBL2489354 0.76 HRH2 (0.55) ALDH1A1
SCHEMBL13545662 0.74
SCHEMBL4565613 0.73 KMT2A (0.43) ALDH1A1TSHRKMT2A
SCHEMBL6157704 0.73 ITGB3 (0.34) ALDH1A1HPGD
SCHEMBL5162056 0.73 FBP1 (0.33)
SCHEMBL6120940 0.73 LMNA (0.34)
SCHEMBL5747523 0.73 RAB9A (0.52) ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999018102-A1 FUNGICIDAL AND ARTHROPODICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-15 WO disclosed