Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435329 | 0.81 | SLC6A3 (0.39) | CYP1A2HRH2HRH1HRH4 | |
| SCHEMBL8480291 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL2489354 | 0.78 | HRH2 (0.55) | CYP1A2HRH2HRH1HRH4 | |
| SCHEMBL13802271 | 0.78 | — | — | |
| SCHEMBL6157704 | 0.75 | ITGB3 (0.34) | — | |
| SCHEMBL5162056 | 0.75 | FBP1 (0.33) | — | |
| SCHEMBL6120940 | 0.75 | LMNA (0.34) | — | |
| SCHEMBL4565613 | 0.75 | KMT2A (0.43) | — | |
| SCHEMBL12806717 | 0.73 | — | — | |
| SCHEMBL6157156 | 0.72 | SHMT2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |