Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | IL1RN | P18510 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294669 | 0.82 | SMN1; SMN2 (0.46) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL13945780 | 0.79 | PGR (0.66) | KMT2AMEN1PKMALDH1A1CA12 | |
| SCHEMBL7572608 | 0.79 | KMT2A (0.61) | KMT2AMEN1PKMALDH1A1CA12 | |
| SCHEMBL9195881 | 0.77 | PTGS2 (0.41) | ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL812663 | 0.77 | PGR (0.82) | KMT2AMEN1PKMALDH1A1CA12 | |
| SCHEMBL9231028 | 0.76 | PGR (0.83) | KMT2AMEN1PKMALDH1A1CA12 | |
| SCHEMBL18405594 | 0.76 | CA4 (0.39) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7826045 | 0.75 | CA2 (0.51) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL9232766 | 0.73 | KMT2A (0.67) | KMT2AMEN1PKMALDH1A1CA12 | |
| SCHEMBL12042475 | 0.73 | ALDH1A1 (0.71) | KMT2AMEN1PKMALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905156-A | POTASSIUM CHANNEL ACTIVATORS AND BRONCHODILATORS | NOVARTIS AG (CH) | 1999-05-18 | — | — | US | disclosed |