Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.51 |
| ▸ | CA12 | O43570 | 12/20 | 0.51 |
| ▸ | CA9 | Q16790 | 12/20 | 0.51 |
| ▸ | CA1 | P00915 | 12/20 | 0.51 |
| ▸ | CA7 | P43166 | 6/20 | 0.51 |
| ▸ | CA4 | P22748 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195881 | 0.84 | PTGS2 (0.41) | ALDH1A1HTTPTGS2PTGS1 | |
| SCHEMBL9294669 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1HTTTSHRPOLB | |
| SCHEMBL9200789 | 0.80 | LMNA (0.56) | ALDH1A1HTTTSHR | |
| SCHEMBL21556124 | 0.80 | ALDH1A1 (0.59) | CA2CA12CA9CA1CA7 | |
| SCHEMBL8483651 | 0.75 | KMT2A (0.54) | CA2CA12CA9CA1ALDH1A1 | |
| SCHEMBL23987218 | 0.74 | CA2 (0.58) | CA2CA12CA9CA1CA7 | |
| SCHEMBL9196159 | 0.74 | ACHE (0.41) | CA2CA9CA1ALDH1A1TSHR | |
| SCHEMBL2008822 | 0.74 | ELANE (0.56) | CA2CA12CA9CA1CA7 | |
| Boric Acid SCHEMBL28014845 | 0.73 | ALDH1A1 (0.47) | CA2CA12CA9CA1CA7 | |
| SCHEMBL7766740 | 0.72 | MAPT (0.44) | CA2CA12CA9CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |