Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MMP16 | P51512 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483651 | 0.82 | KMT2A (0.54) | SMN1; SMN2HTTPKMMAPTALDH1A1 | |
| SCHEMBL9195881 | 0.81 | PTGS2 (0.41) | SMN1; SMN2HTTELANEALDH1A1 | |
| SCHEMBL23075718 | 0.81 | HTR6 (0.54) | SMN1; SMN2HTTHTR6PKMHSD11B1 | |
| SCHEMBL18405594 | 0.80 | CA4 (0.39) | ELANEPPARAMAPTALDH1A1MEN1 | |
| SCHEMBL7826045 | 0.80 | CA2 (0.51) | HTTPOLBALDH1A1TSHR | |
| SCHEMBL9534370 | 0.79 | HTR6 (0.58) | HTTHTR6HSD11B1POLBGAA | |
| SCHEMBL5308750 | 0.78 | LTA4H (0.47) | SMN1; SMN2HTTPPARAALDH1A1MEN1 | |
| SCHEMBL9200789 | 0.77 | LMNA (0.56) | SMN1; SMN2HTTELANEMAPTALDH1A1 | |
| SCHEMBL22295587 | 0.77 | HTT (0.62) | SMN1; SMN2HTTHTR6PKMHSD11B1 | |
| SCHEMBL22295637 | 0.77 | HTT (0.62) | SMN1; SMN2HTTHTR6PKMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364878-A | Antiasthmatics; urogenital disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0351720-B1 | Use of substituted 3,4-dihydro-2H-benzopyrans as medicaments against obstructive disorders of the lung | HOECHST AG (DE) | 1994-08-24 | — | — | EP | disclosed |
| EP-0560399-A1 | Use of substituted 3,4-dihydro-2H-benzopyrans as medicament against disorders of the urethra | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| US-5043344-A | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |
| EP-0351720-A2 | Use of substituted 3,4-dihydro-2H-benzopyrans as medicaments against obstructive disorders of the lung | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0337179-A1 | Unsaturated N-benzopyranyllactams | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-18 | — | — | EP | disclosed |