Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482557 | 0.93 | ALDH1A1 (0.49) | PTGESRAB9AKMT2AMAPTLMNA | |
| SCHEMBL5043206 | 0.81 | HPGD (0.46) | KMT2AMAPTLMNAMAPK1MEN1 | |
| SCHEMBL29295506 | 0.80 | L3MBTL1 (0.52) | KMT2AMEN1HPGDALDH1A1CYP1A2 | |
| SCHEMBL18769941 | 0.79 | PTPRC (0.54) | RAB9AKMT2AMAPTMEN1HPGD | |
| SCHEMBL30016479 | 0.79 | PTPRC (0.54) | RAB9AKMT2AMAPTMEN1HPGD | |
| SCHEMBL30016005 | 0.78 | PTPRC (0.68) | RAB9AKMT2AMAPTMEN1RXFP1 | |
| SCHEMBL8484733 | 0.76 | ALDH1A1 (0.49) | RAB9AKMT2AMAPTLMNAMAPK1 | |
| SCHEMBL28109773 | 0.76 | KMT2A (0.64) | KMT2AMEN1RXFP1HPGDALDH1A1 | |
| SCHEMBL20644280 | 0.75 | FFAR1 (0.57) | RAB9AKMT2AMAPTMEN1RXFP1 | |
| SCHEMBL4679518 | 0.74 | MAPT (0.63) | PTGESRAB9AKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067991-C | Aminoalkyl subsetd. benzo-heterocyclic compounds | HOFFMANN LA ROCHE (CH) | 2001-07-04 | — | — | CN | disclosed |
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |
| CN-1161328-A | Aminoalkyl subsetd. benzo-heterocyclic compounds | HOFFMANN LA ROCHE (CH) | 1997-10-08 | — | — | CN | disclosed |
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |