Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578621 | 0.80 | RXRA (0.48) | RXRANR1H2NR1H3PTGS2KCNK3 | |
| SCHEMBL9208779 | 0.80 | PTGS2 (0.51) | PTGS2AOC3PTGS1CHRNA7 | |
| SCHEMBL9199556 | 0.76 | AOC3 (0.65) | PTGS2AOC3PTGS1CHRNA7 | |
| SCHEMBL9202470 | 0.73 | PTGS2 (0.51) | PTGS2AOC3PTGS1CHRNA7 | |
| SCHEMBL9208216 | 0.72 | PTGS2 (0.49) | RXRANR1H2NR1H3PTGS2AOC3 | |
| SCHEMBL8491097 | 0.70 | RXRA (0.56) | RXRANR1H2NR1H3PTGS2PTGS1 | |
| SCHEMBL27330300 | 0.70 | PTGS2 (0.55) | PTGS2AOC3PTGS1CHRNA7 | |
| SCHEMBL9744795 | 0.70 | PTGS2 (0.55) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL9212272 | 0.70 | MARS1 (0.55) | PTGS2AOC3PTGS1CHRNA7 | |
| SCHEMBL9744791 | 0.70 | PTGS2 (0.46) | PTGS2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999025695-A1 | 5-ARYLPYRAZOLE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-27 | — | — | WO | disclosed |