Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.43 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208216 | 0.86 | PTGS2 (0.49) | PTGS2ALDH1A1CHRNA7ALOX5MAPT | |
| SCHEMBL9209551 | 0.83 | ALOX5 (0.60) | PTGS2CA9CHRNA7ALOX5 | |
| SCHEMBL9744795 | 0.82 | PTGS2 (0.55) | PTGS2CA9CHRNA7 | |
| SCHEMBL9208779 | 0.79 | PTGS2 (0.51) | PTGS2CHRNA7 | |
| SCHEMBL9200880 | 0.78 | PTGS2 (0.63) | PTGS2CA9CHRNA7ALOX5 | |
| SCHEMBL9204576 | 0.78 | PTGS2 (0.59) | PTGS2CHRNA7ALOX5 | |
| SCHEMBL9208261 | 0.78 | CHRNA7 (0.51) | PTGS2CHRNA7ALOX5 | |
| SCHEMBL27330300 | 0.77 | PTGS2 (0.55) | PTGS2CA9CHRNA7ALOX5 | |
| SCHEMBL9199556 | 0.77 | AOC3 (0.65) | PTGS2CHRNA7 | |
| SCHEMBL9202470 | 0.76 | PTGS2 (0.51) | PTGS2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134142-A | PYRAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |