Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.37 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | DRD3 | P35462 | 7/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489168 | 0.88 | SLC6A4 (0.39) | ALOX5SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL8486794 | 0.83 | SLC6A4 (0.40) | ALOX5SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL8491694 | 0.80 | HTR2A (0.40) | ALOX5SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL6678093 | 0.73 | SLC6A4 (0.44) | ALOX5SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL6678094 | 0.73 | SLC6A4 (0.44) | ALOX5SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL8489828 | 0.73 | MGAM (0.46) | ALOX5HTR2ADRD2DRD3 | |
| SCHEMBL8487685 | 0.73 | DRD2 (0.41) | ALOX5DRD2MTNR1AMTNR1BHTR1A | |
| SCHEMBL8488076 | 0.71 | MTNR1B (0.39) | ALOX5MTNR1AMTNR1B | |
| SCHEMBL8485551 | 0.71 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR2ADRD2 | |
| SCHEMBL8487182 | 0.71 | MTNR1A (0.39) | ALOX5MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |