Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 12/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488140 | 0.90 | GABRG2 (0.38) | GABRG2GABRB3GABRA5SLC22A12GABRA1 | |
| SCHEMBL8525146 | 0.85 | HCRTR2 (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL8525066 | 0.84 | HCRTR2 (0.32) | KDM4EMEN1USP2LMNAMAPT | |
| SCHEMBL8524133 | 0.84 | L3MBTL1 (0.34) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL8525657 | 0.80 | HCRTR2 (0.42) | GABRG2GABRB3GABRA5KDM4EMEN1 | |
| SCHEMBL8490765 | 0.79 | L3MBTL1 (0.35) | GABRG2GABRB3GABRA5KDM4EMEN1 | |
| SCHEMBL8524884 | 0.79 | LMNA (0.34) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL8391480 | 0.78 | ALDH1A1 (0.34) | KDM4EMEN1USP2LMNAMAPT | |
| SCHEMBL8490014 | 0.78 | HTT (0.38) | KDM4EMEN1USP2LMNAMAPT | |
| SCHEMBL8492298 | 0.77 | L3MBTL1 (0.34) | GABRG2GABRB3GABRA5KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |