Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668402 | 0.82 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL29724092 | 0.82 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL29724110 | 0.79 | ALDH1A1 (0.47) | GPR174MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8487393 | 0.76 | NOTUM (0.34) | MAPTALDH1A1HPGDTSHRLMNA | |
| SCHEMBL28697213 | 0.74 | MAPT (0.49) | GPR174MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL22621295 | 0.73 | GPR174 (1.00) | GPR174MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28933806 | 0.70 | L3MBTL1 (0.71) | GPR174MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11072823 | 0.70 | TSHR (0.55) | MAPTALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL28017211 | 0.70 | BAZ2B (0.46) | MAPTALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL22621305 | 0.69 | GPR174 (1.00) | GPR174MAPTALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914401-A | Methods for the manufacture of quinolone carboxylic acids derivatives and intermediates thereof | APOTEX, INC. (CA) | 1999-06-22 | — | — | US | disclosed |