Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668402 | 0.84 | MAPT (0.48) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL29724092 | 0.84 | MAPT (0.48) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL28673653 | 0.80 | MAPT (0.47) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL29724110 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28294663 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL8488373 | 0.74 | GPR174 (0.58) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL8487393 | 0.74 | NOTUM (0.34) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL13455887 | 0.73 | LMNA (0.38) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL22774193 | 0.68 | TOP2A (0.50) | MAPTALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL29576674 | 0.68 | TOP2A (0.50) | MAPTALDH1A1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816959-A | Isochrysine analogue prepared from enrofloxacin as raw material and preparation method and application thereof | 郑州工业应用技术学院 | 2021-12-21 | — | — | CN | disclosed |