Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724092 | 1.00 | MAPT (0.48) | MAPTALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL28294663 | 0.86 | ALDH1A1 (0.47) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL29724110 | 0.86 | ALDH1A1 (0.47) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL28697213 | 0.84 | MAPT (0.49) | MAPTALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL8487393 | 0.83 | NOTUM (0.34) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL8488373 | 0.82 | GPR174 (0.58) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL22774193 | 0.78 | TOP2A (0.50) | MAPTALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL29576674 | 0.78 | TOP2A (0.50) | MAPTALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL4814415 | 0.77 | CRBN (0.49) | MAPTALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL4338990 | 0.75 | PARK7 (0.50) | MAPTALDH1A1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816958-A | Isoleucinine analogue prepared from pefloxacin as raw material, and preparation method and application thereof | 郑州工业应用技术学院 | 2021-12-21 | — | — | CN | claimed |
| CN-109776411-B | Nitrogen mustard carbostyril derivative and preparation method and application thereof | 石家庄学院 | 2022-06-07 | — | — | CN | disclosed |
| CN-113816958-A | Isoleucinine analogue prepared from pefloxacin as raw material, and preparation method and application thereof | 郑州工业应用技术学院 | 2021-12-21 | — | — | CN | disclosed |