SCHEMBL849424

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10290708	0.86	PNMT (0.45)	ALDH1A1CA2CA12CA1CA9
	SCHEMBL16492321	0.76	ALDH1A1 (0.65)	ALDH1A1CA2CA1CA9CCR2
	SCHEMBL849323	0.74	TSHR (0.59)	ALDH1A1CA2CA12CA9MAPK1
	SCHEMBL30309623	0.73	ALDH1A1 (0.56)	ALDH1A1NPC1RAB9AMAPK1MEN1
	SCHEMBL20743599	0.73	ALDH1A1 (0.56)	ALDH1A1NPC1RAB9AMAPK1MEN1
	SCHEMBL2472645	0.71	MMP1 (0.57)	ALDH1A1KMT2A
	SCHEMBL17717286	0.71	IDO1 (0.40)	ALDH1A1CCR2IDO1
	SCHEMBL710212	0.71	LMNA (0.59)	ALDH1A1CA2CA12CA1CA9
	SCHEMBL117930	0.70	PKM (0.65)	ALDH1A1CA2CA12CA1CA9
	SCHEMBL849361	0.70	IDO1 (0.44)	ALDH1A1CA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.