Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489111 | 0.86 | CACNA1B (0.38) | LMNAEEDPOLBBCAT2CACNA1B | |
| SCHEMBL8495604 | 0.79 | POLB (0.36) | LMNAEEDPOLBBCAT2HRH1 | |
| SCHEMBL8489221 | 0.76 | SLC9A1 (0.40) | LMNAEEDHRH1CCR3CACNA1B | |
| SCHEMBL8606607 | 0.71 | LMNA (0.43) | LMNAEEDBCAT2HRH1CCR3 | |
| SCHEMBL8606545 | 0.69 | LMNA (0.40) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8607785 | 0.65 | LMNA (0.37) | LMNAEEDPOLBBCAT2HRH1 | |
| SCHEMBL8608675 | 0.65 | LMNA (0.38) | LMNAEEDBCAT2HRH1CCR3 | |
| SCHEMBL8388424 | 0.64 | MGLL (0.42) | LMNAPOLBMGLL | |
| SCHEMBL8608708 | 0.63 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8762938 | 0.62 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |