Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 9/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606545 | 0.86 | LMNA (0.40) | LMNAEEDMGLLBCAT2CACNA1B | |
| SCHEMBL8607666 | 0.79 | TSHR (0.37) | LMNAMGLLKDM4EALDH1A1 | |
| SCHEMBL8605528 | 0.78 | LMNA (0.42) | LMNAEEDBCAT2CACNA1BKDM4E | |
| SCHEMBL8608675 | 0.74 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8608708 | 0.71 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8494381 | 0.71 | LMNA (0.37) | LMNAEEDMGLLBCAT2CACNA1B | |
| SCHEMBL8489221 | 0.71 | SLC9A1 (0.40) | LMNAEEDMGLLCACNA1BSLC9A1 | |
| SCHEMBL8607785 | 0.70 | LMNA (0.37) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8606612 | 0.69 | LMNA (0.38) | LMNAEEDBCAT2HRH1CCR3 | |
| SCHEMBL8762938 | 0.66 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |