SCHEMBL8499233

SCHEMBL8499233

CN(C)OCCOc1cccc(N(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 8/20 0.45
MTNR1B P49286 8/20 0.45
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ESR1 P03372 2/20 0.43
TSHR P16473 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943678 0.88 KCNA3 (0.46) MTNR1AMTNR1BKDM4ELMNAMAPK1
SCHEMBL8944001 0.83 KCNA3 (0.56) MTNR1AMTNR1BTSHRKMT2A
SCHEMBL8944183 0.83 DRD2 (0.44) MTNR1AMTNR1BLMNAMAPK1L3MBTL1
SCHEMBL21028983 0.82 LTA4H (0.58) MTNR1AMTNR1BTSHRKMT2A
SCHEMBL8495228 0.80 L3MBTL1 (0.40) MTNR1AMTNR1BKDM4ELMNAMAPK1
SCHEMBL18431943 0.79 MAPK1 (0.41) MTNR1AMTNR1BKDM4ELMNAMAPK1
SCHEMBL10339364 0.78 APP (0.55) MTNR1AMTNR1BLMNAMAPK1L3MBTL1
SCHEMBL10065561 0.78 CYP3A4 (0.52) KDM4ELMNAMAPK1L3MBTL1TSHR
SCHEMBL8497744 0.78 CHRNA7 (0.55) MTNR1AMTNR1BKDM4ECHRNB2CHRNA4
SCHEMBL8943634 0.77 DRD2 (0.49) MTNR1AMTNR1BLMNAMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919608-A EXPOSING TO ELECTROMAGNETIC RADIATION A COMPOSITION COMPRISING CATIONIC ELECTRON ACCEPTOR, SENSITIZING DYE, AND SUPERSENSITIZER POLAROID CORPORATION (US) 1999-07-06 US disclosed