SCHEMBL8943634

SCHEMBL8943634

COc1ccc(N(c2ccccc2)c2cccc(OCCCCOc3cccc(N(c4ccccc4)c4ccc(OC)cc4)c3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
LTA4H P09960 2/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
MAPT P10636 2/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KCNA3 P22001 1/20 0.44
MAOB P27338 2/20 0.44
PPARG P37231 2/20 0.44
KCNH2 Q12809 1/20 0.43
HPGD P15428 1/20 0.43
ATM Q13315 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943912 0.89 DRD2 (0.56) DRD2DRD4DRD3LTA4HL3MBTL1
SCHEMBL8944001 0.89 KCNA3 (0.56) LTA4HMTNR1AMTNR1BKCNA3KMT2A
SCHEMBL21028983 0.87 LTA4H (0.58) LTA4HMTNR1AMTNR1BKCNA3CYP1A2
SCHEMBL13385303 0.87 CA4 (0.52) LTA4HMTNR1AMTNR1BMAOBHPGD
SCHEMBL8943946 0.87 MAOB (0.48) DRD2DRD4DRD3L3MBTL1MAPT
SCHEMBL8943774 0.85 L3MBTL1 (0.57) DRD2DRD4DRD3LTA4HL3MBTL1
SCHEMBL10445865 0.85 MTNR1A (0.47) DRD2DRD4DRD3LTA4HMTNR1A
SCHEMBL8943641 0.84 LTA4H (0.58) DRD2DRD4DRD3LTA4HL3MBTL1
SCHEMBL8943988 0.84 L3MBTL1 (0.59) DRD2DRD4DRD3LTA4HL3MBTL1
SCHEMBL8944175 0.84 L3MBTL1 (0.59) DRD2DRD4DRD3LTA4HL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed