SCHEMBL8943678

SCHEMBL8943678

c1ccc(N(c2ccccc2)c2cccc(OCCOc3cccc(N(c4ccccc4)c4ccccc4)c3)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.46
MAPK1 P28482 2/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 1/20 0.43
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
MAOB P27338 2/20 0.42
MAOA P21397 1/20 0.42
KMT2A Q03164 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ALDH1A1 P00352 1/20 0.42
RECQL P46063 1/20 0.42
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
LTA4H P09960 1/20 0.41
F2 P00734 1/20 0.41
PLG P00747 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944001 0.94 KCNA3 (0.56) KCNA3TSHRMTNR1AMTNR1BKMT2A
SCHEMBL8944183 0.90 DRD2 (0.44) MAPK1LMNAL3MBTL1TSHRMTNR1A
SCHEMBL21028983 0.89 LTA4H (0.58) KCNA3TSHRMTNR1AMTNR1BKMT2A
SCHEMBL8499233 0.88 MTNR1A (0.45) MAPK1LMNAL3MBTL1TSHRMTNR1A
SCHEMBL8495228 0.87 L3MBTL1 (0.40) MAPK1LMNAL3MBTL1TSHRMTNR1A
SCHEMBL18431943 0.86 MAPK1 (0.41) MAPK1LMNAL3MBTL1TSHRMTNR1A
SCHEMBL10065561 0.85 CYP3A4 (0.52) MAPK1LMNAL3MBTL1TSHRKMT2A
SCHEMBL8500323 0.84 CHRM2 (0.43) KCNA3MAPK1LMNAMTNR1AMTNR1B
SCHEMBL8943634 0.84 DRD2 (0.49) KCNA3MAPK1LMNAL3MBTL1TSHR
SCHEMBL10445865 0.84 MTNR1A (0.47) KCNA3TSHRMTNR1AMTNR1BLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed