SCHEMBL8944183

SCHEMBL8944183

Cc1ccc(N(c2ccccc2)c2cccc(OCCOc3cccc(N(c4ccccc4)c4ccc(C)cc4)c3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.44
DRD4 P21917 5/20 0.44
DRD3 P35462 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
F2 P00734 1/20 0.41
TSHR P16473 1/20 0.41
MAOB P27338 2/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
MAPT P10636 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10445865 0.94 MTNR1A (0.47) DRD2DRD4DRD3TSHRMTNR1A
SCHEMBL11887991 0.92 DRD2 (0.48) DRD2DRD4DRD3F2TSHR
SCHEMBL8943678 0.90 KCNA3 (0.46) L3MBTL1TDP1KMT2ALMNAMAPK1
SCHEMBL2623406 0.90 MTNR1A (0.44) DRD2DRD4DRD3TSHRMTNR1A
SCHEMBL8943946 0.89 MAOB (0.48) DRD2DRD4DRD3L3MBTL1TDP1
SCHEMBL11887992 0.87 MAOB (0.42) DRD2DRD4DRD3F2MAOB
SCHEMBL8944001 0.84 KCNA3 (0.56) KMT2ATSHRMTNR1AMTNR1B
SCHEMBL21028983 0.83 LTA4H (0.58) KMT2ATSHRMTNR1AMTNR1B
SCHEMBL14340638 0.83 ACHE (0.50) RAB9ATSHRMAOBMTNR1AMTNR1B
SCHEMBL18431943 0.83 MAPK1 (0.41) L3MBTL1LMNAMAPK1TSHRMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed