SCHEMBL849975

SCHEMBL849975

COCCCCCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
TSHR P16473 6/20 0.60
LMNA P02545 2/20 0.60
NFKB1 P19838 1/20 0.60
PMP22 Q01453 1/20 0.60
GPR84 Q9NQS5 8/20 0.54
PPARG P37231 7/20 0.54
PPARD Q03181 7/20 0.54
PPARA Q07869 7/20 0.54
HDAC11 Q96DB2 5/20 0.54
PTPN1 P18031 3/20 0.54
TLR2 O60603 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
FABP4 P15090 2/20 0.54
FFAR1 O14842 2/20 0.54
FFAR4 Q5NUL3 2/20 0.54
SLC22A6 Q4U2R8 1/20 0.54
SLC22A8 Q8TCC7 1/20 0.54
MEN1 O00255 1/20 0.54
ESR1 P03372 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26302700 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL2553415 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL1285325 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL18992918 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL7197969 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL2556960 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL3121839 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL2137289 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL21655426 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL7199372 1.00 ALDH1A1 (1.00) ALDH1A1TSHRLMNANFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-09-02 US disclosed
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2025-07-17 US disclosed
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-06-10 US disclosed
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-04-01 US disclosed
US-12151995-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2024-11-26 US disclosed
US-20240124388-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2024-04-18 US disclosed
EP-4286012-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2023-12-06 EP disclosed
US-20120270838-A1 SPIROIMIDAZOLONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2012-10-25 US disclosed
US-20120270838-A1 SPIROIMIDAZOLONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2012-10-25 US disclosed
US-20120270838-A1 SPIROIMIDAZOLONE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2012-10-25 US disclosed
EP-2433940-A1 SPIROIMIDAZOLONE DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 2012-03-28 EP disclosed
EP-2433940-A1 SPIROIMIDAZOLONE DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 2012-03-28 EP disclosed
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed
WO-2008083029-A2 DEVICE PACKAGE AND METHOD OF MAKING A DEVICE PACKAGE TEXAS INSTRUMENTS INCORPORATED (US) 2008-07-10 WO disclosed
US-20080160268-A1 DEVICE PACKAGE AND METHOD OF MAKING A DEVICE PACKAGE TEXAS INSTRUMENTS INCORPORATED 2008-07-03 US disclosed
EP-1100804-A1 TIN POLYOXAALKANECARBOXYLATES AND COMPOSITIONS CONTAINING THEM PHARMACHEMIE B.V. (NL) 2001-05-23 EP disclosed
WO-2000006583-A1 TIN POLYOXAALKANECARBOXYLATES AND COMPOSITIONS CONTAINING THEM PHARMACHEMIE B.V. (NL) 2000-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885TSHR 3089/4885LMNA 1539/4885
US-20120270838-A1 SPIROIMIDAZOLONE DERIVATIVE WNK3, REN, SGK3 ALDH1A1 836/4885TSHR 914/4885LMNA 2006/4885
US-12151995-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885TSHR 3089/4885LMNA 1539/4885
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885TSHR 3089/4885LMNA 1539/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP ALDH1A1 4429/4885TSHR 4134/4885LMNA 455/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 ALDH1A1 4755/4885TSHR 540/4885LMNA 1487/4885
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 ALDH1A1 4530/4885TSHR 3089/4885LMNA 1539/4885
US-20240124388-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 ALDH1A1 4530/4885TSHR 3089/4885LMNA 1539/4885
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 ALDH1A1 4530/4885TSHR 3089/4885LMNA 1539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.