Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262710 | 0.80 | MEN1 (0.71) | LMNAMAPTMEN1KMT2AFNTA | |
| SCHEMBL6843471 | 0.78 | LMNA (0.76) | LMNAMAPTMAPK1TDP1MEN1 | |
| SCHEMBL1983443 | 0.74 | NOX1 (1.00) | LMNAMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL7566877 | 0.72 | HTR1A (0.70) | LMNAMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL628325 | 0.72 | MAOA (0.55) | LMNAMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL8869747 | 0.71 | LMNA (0.64) | LMNAMAPTMAPK1TDP1MEN1 | |
| SCHEMBL31014072 | 0.69 | MEN1 (1.00) | LMNAMAPTMEN1KMT2AFNTA | |
| SCHEMBL179882 | 0.69 | MEN1 (1.00) | LMNAMAPTMEN1KMT2AFNTA | |
| SCHEMBL628328 | 0.69 | MAOA (0.68) | LMNAMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL8520671 | 0.69 | ITGB2 (0.62) | LMNAMAPTMAPK1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965510-A | USING AGENT COMPRISING AN ORGANIC CHEMICAL COMPOUND CONSISTING OF AT LEAST TWO AROMATIC RINGS, OF WHICH AROMATIC RINGS AT LEAST ONE RING IS SUBSTITUTED WITH NITROGEN AND OXYGEN OR SULFUR; WASHING, BLEACHING | NOVO NORDISK A/S (DK) | 1999-10-12 | — | — | US | claimed |