Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501042 | 0.90 | ESR1 (0.40) | L3MBTL1TDP1ESR1ESR2KDM4E | |
| SCHEMBL8500428 | 0.90 | ESR1 (0.41) | L3MBTL1TDP1ESR1ESR2ALDH1A1 | |
| SCHEMBL8500327 | 0.89 | ESR1 (0.42) | L3MBTL1TDP1ESR1ESR2KDM4E | |
| SCHEMBL8497554 | 0.88 | L3MBTL1 (0.51) | L3MBTL1TDP1ESR1ESR2MMP3 | |
| SCHEMBL8498114 | 0.88 | ESR1 (0.46) | ESR1ESR2KDM4ENPC1RAB9A | |
| SCHEMBL8499012 | 0.86 | NPBWR1 (0.40) | L3MBTL1TDP1ESR1ESR2KDM4E | |
| SCHEMBL8501225 | 0.85 | ESR1 (0.43) | L3MBTL1TDP1ESR1ESR2KDM4E | |
| SCHEMBL8500300 | 0.83 | CYP1A2 (0.40) | L3MBTL1TDP1ESR1ESR2GAA | |
| SCHEMBL8500218 | 0.83 | THRA (0.36) | L3MBTL1TDP1ESR1ESR2ALDH1A1 | |
| SCHEMBL8499724 | 0.82 | ESR1 (0.45) | L3MBTL1TDP1ESR1ESR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |