Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565064 | 0.88 | SLC6A2 (0.38) | OPRD1AAK1SLC6A2SLC6A4 | |
| SCHEMBL8500691 | 0.73 | SLC6A2 (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL2800413 | 0.72 | L3MBTL1 (0.42) | SLC6A2SLC6A4 | |
| SCHEMBL7799840 | 0.71 | POLB (0.41) | MMP1MMP3MMP9OPRD1SLC6A2 | |
| SCHEMBL8703070 | 0.69 | ITGA4 (0.42) | MMP1MMP3MMP9ITGB3 | |
| SCHEMBL19260910 | 0.67 | OPRM1 (0.45) | SLC6A2SLC6A4 | |
| SCHEMBL7985858 | 0.67 | KDM4E (0.49) | — | |
| SCHEMBL22373000 | 0.66 | ADRB2 (0.43) | FAAHITGB3ITGA2BADRB2ADRB1 | |
| SCHEMBL8129250 | 0.66 | CPN1 (0.50) | OPRD1ITGB3ITGA2B | |
| SCHEMBL22374186 | 0.65 | MAPT (0.42) | FAAHCES1ITGB3ITGA2BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |