Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505745 | 0.88 | KMT2A (0.44) | KMT2ANPBWR1MAPTRAB9ACYP19A1 | |
| SCHEMBL8501886 | 0.88 | NPBWR1 (0.45) | KMT2ANPBWR1MAPTRAB9ACYP19A1 | |
| SCHEMBL8503193 | 0.88 | NR4A1 (0.40) | KMT2AMAPTRAB9ACYP19A1 | |
| SCHEMBL8504945 | 0.85 | NPBWR1 (0.39) | KMT2ANPBWR1RAB9ACYP19A1HPGD | |
| SCHEMBL7589793 | 0.75 | KMT2A (0.58) | KMT2AMAPTRAB9AHPGD | |
| SCHEMBL27501601 | 0.75 | NPBWR1 (0.56) | NPBWR1MAPTCMA1 | |
| SCHEMBL8504856 | 0.73 | ALDH1A1 (0.47) | KMT2AMAPTRAB9ACYP19A1HPGD | |
| SCHEMBL8501895 | 0.73 | HTT (0.40) | KMT2AMAPTRAB9AHPGD | |
| SCHEMBL7580985 | 0.72 | KMT2A (0.55) | KMT2AMAPTRAB9AHPGD | |
| SCHEMBL7583543 | 0.72 | KMT2A (0.65) | KMT2AMAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |