Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501886 | 0.89 | NPBWR1 (0.45) | KMT2ANPBWR1MAPK14CYP19A1CYP11B1 | |
| SCHEMBL8504853 | 0.88 | KMT2A (0.49) | KMT2ANPBWR1MAPK14CYP19A1MAPT | |
| SCHEMBL8501880 | 0.76 | ALDH1A1 (0.35) | KMT2AMAPTTP53RAB9ANPC1 | |
| SCHEMBL8503193 | 0.75 | NR4A1 (0.40) | KMT2ACYP19A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL8504945 | 0.73 | NPBWR1 (0.39) | KMT2ANPBWR1CYP19A1SMN1; SMN2RAB9A | |
| SCHEMBL27501601 | 0.73 | NPBWR1 (0.56) | NPBWR1MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8505747 | 0.72 | KMT2A (0.45) | KMT2ACYP11B1CYP11B2MAPTSMN1; SMN2 | |
| SCHEMBL8526361 | 0.72 | MAPT (0.43) | KMT2AMAPTTP53MEN1ALDH1A1 | |
| SCHEMBL7583160 | 0.70 | KMT2A (0.42) | KMT2AMAPTSMN1; SMN2TP53RAB9A | |
| SCHEMBL9360054 | 0.70 | KMT2A (0.59) | KMT2AMAPTSMN1; SMN2TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |