Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669688 | 0.93 | DRD2 (0.39) | DRD2DRD4DRD3CHRM1NPSR1 | |
| SCHEMBL8714745 | 0.93 | CHRM1 (0.41) | DRD2DRD4DRD3CHRM1KMT2A | |
| SCHEMBL8501237 | 0.91 | MTTP (0.36) | DRD2DRD4DRD3CHRM1KMT2A | |
| SCHEMBL8501050 | 0.88 | MTTP (0.36) | DRD2DRD4DRD3CHRM1KMT2A | |
| SCHEMBL8665881 | 0.85 | DRD2 (0.37) | DRD2DRD4DRD3CHRM1KMT2A | |
| SCHEMBL8480929 | 0.84 | DRD2 (0.44) | DRD2DRD4DRD3KMT2AMAPT | |
| SCHEMBL8666097 | 0.82 | DRD2 (0.36) | DRD2DRD4DRD3CHRM1KMT2A | |
| SCHEMBL8503794 | 0.82 | DRD2 (0.38) | DRD2DRD4DRD3KMT2AMAPT | |
| SCHEMBL8500999 | 0.80 | CTSL (0.37) | DRD2DRD4DRD3NAAAOPRM1 | |
| SCHEMBL8573842 | 0.79 | TRPV1 (0.43) | KMT2AMAPTMEN1NAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |