Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669688 | 0.96 | DRD2 (0.39) | CHRM1DRD2DRD4DRD3CARM1 | |
| SCHEMBL8502239 | 0.93 | DRD2 (0.39) | CHRM1DRD2DRD4DRD3GAA | |
| SCHEMBL8665881 | 0.88 | DRD2 (0.37) | CHRM1DRD2DRD4DRD3CARM1 | |
| SCHEMBL8666097 | 0.85 | DRD2 (0.36) | CHRM1DRD2DRD4DRD3CARM1 | |
| SCHEMBL8480929 | 0.84 | DRD2 (0.44) | DRD2DRD4DRD3HPGDKMT2A | |
| SCHEMBL8501237 | 0.84 | MTTP (0.36) | CHRM1DRD2DRD4DRD3GAA | |
| SCHEMBL8480412 | 0.83 | DRD2 (0.37) | DRD2DRD4DRD3GAAHPGD | |
| SCHEMBL8501050 | 0.82 | MTTP (0.36) | CHRM1DRD2DRD4DRD3GAA | |
| SCHEMBL8668074 | 0.80 | DRD2 (0.37) | DRD2DRD4DRD3GAAHPGD | |
| SCHEMBL8675068 | 0.78 | L3MBTL1 (0.42) | DRD2DRD4DRD3GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |