Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714745 | 0.96 | CHRM1 (0.41) | DRD2DRD4DRD3CARM1PRMT6 | |
| SCHEMBL8502239 | 0.93 | DRD2 (0.39) | DRD2DRD4DRD3CHRM1NPSR1 | |
| SCHEMBL8665881 | 0.91 | DRD2 (0.37) | DRD2DRD4DRD3AKT1CARM1 | |
| SCHEMBL8666097 | 0.89 | DRD2 (0.36) | DRD2DRD4DRD3MTNR1AMTNR1B | |
| SCHEMBL8501237 | 0.85 | MTTP (0.36) | DRD2DRD4DRD3CHRM1NPSR1 | |
| SCHEMBL8480929 | 0.83 | DRD2 (0.44) | DRD2DRD4DRD3NPSR1KDM4E | |
| SCHEMBL8501050 | 0.82 | MTTP (0.36) | DRD2DRD4DRD3CHRM1 | |
| SCHEMBL8668074 | 0.82 | DRD2 (0.37) | DRD2DRD4DRD3NPSR1NAMPT | |
| SCHEMBL8675068 | 0.81 | L3MBTL1 (0.42) | DRD2DRD4DRD3NPSR1KDM4E | |
| SCHEMBL8665519 | 0.80 | CCR3 (0.40) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |