SCHEMBL850353

SCHEMBL850353

CCCCCCCCCCC(C)SC(=S)SCC#N

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
OPRM1 P35372 1/20 0.31
GPR84 Q9NQS5 3/20 0.30
FDPS P14324 3/20 0.30
FFAR1 O14842 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3755642 0.84 LMNA (0.32) SPHK1LMNATSHRGPR84FDPS
SCHEMBL21409835 0.82 SPHK1 (0.42) SPHK1LMNAACE2OPRM1GPR84
SCHEMBL27970261 0.82 SPHK1 (0.34) SPHK1LMNAACE2OPRM1GPR84
SCHEMBL851799 0.78 SPHK1 (0.32) SPHK1LMNA
SCHEMBL21465717 0.76 EPHX1 (0.33) TSHR
SCHEMBL27130884 0.75
SCHEMBL851466 0.74 THRB (0.33) LMNATSHRCA1
SCHEMBL3833267 0.72 SPHK1 (0.39) SPHK1LMNAACE2OPRM1GPR84
SCHEMBL6035114 0.71 CSNK1E (0.42)
Potassium Ion SCHEMBL11605840 0.70 CA1 (0.41) SPHK1LMNAACE2OPRM1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181209-A Nano-gold composite material containing arginine methyl ester copolymer and preparation method thereof 武汉理工大学 2022-10-14 CN claimed
EP-2432808-B1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2015-10-21 EP claimed
EP-2432808-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS Novartis AG (CH) 2012-03-28 EP claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 WO claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed
US-7408013-B2 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AT) 2008-08-05 US claimed
US-20070123729-A1 Synthesis of trithiocarbonates E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-31 US claimed
EP-1673662-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE POLYMERS AND PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-28 EP claimed
US-20050112495-A1 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-05-26 US claimed
WO-2005031462-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE POLYMERS AND PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-07 WO claimed
EP-3532519-B1 AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS ALCON INC (CH) 2026-01-21 EP disclosed
WO-2025047052-A1 ADHESIVE AGENT COMPOSITION AND ADHESIVE SHEET 株式会社レゾナック 2025-03-06 WO disclosed
WO-2025013711-A1 VINYL AMIDE COPOLYMER AND METHOD FOR PRODUCING SAME, VINYL AMIDE COPOLYMER COMPOSITION, COATING AGENT FOR MEDICAL USE, COATING MATERIAL FOR MEDICAL USE, AND MEDICAL DEVICE 株式会社クラレ 2025-01-16 WO disclosed
WO-2023176834-A1 ADHESIVE COMPOSITION, ADHESIVE LAYER, AND ADHESIVE SHEET 日東電工株式会社 2023-09-21 WO disclosed
WO-2023176833-A1 ADHESIVE AGENT COMPOSITION, ADHESIVE AGENT LAYER, AND ADHESIVE SHEET 日東電工株式会社 2023-09-21 WO disclosed
EP-1664927-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE ACRYLIC POLYMERS, PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-07 EP disclosed
US-20050119378-A1 Controlled radical polymerization; photoresists with high transparency at 157-248 nm and good resolution DUPONT ELECTRONICS, INC. 2005-06-02 US disclosed
US-20050112495-A1 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-05-26 US disclosed
WO-2005031461-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE ACRYLIC POLYMERS, PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-07 WO disclosed
WO-2005031462-A1 LOW-POLYDISPERSITY PHOTOIMAGEABLE POLYMERS AND PHOTORESISTS AND PROCESSES FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 SPHK1 4158/4885LMNA 1029/4885TSHR 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.