Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21409835 | 0.80 | SPHK1 (0.42) | SPHK1LMNA | |
| SCHEMBL27970261 | 0.80 | SPHK1 (0.34) | SPHK1LMNA | |
| SCHEMBL850353 | 0.78 | SPHK1 (0.33) | SPHK1LMNA | |
| SCHEMBL19253053 | 0.77 | CA2 (0.35) | CA2 | |
| SCHEMBL23398355 | 0.74 | FAAH (0.31) | — | |
| SCHEMBL28097311 | 0.71 | FFAR4 (0.33) | — | |
| SCHEMBL2232709 | 0.70 | NOS3 (0.35) | — | |
| SCHEMBL3833267 | 0.70 | SPHK1 (0.39) | SPHK1LMNA | |
| SCHEMBL13858781 | 0.68 | CA1 (0.42) | SPHK1LMNACA2 | |
| Potassium Ion SCHEMBL11605840 | 0.68 | CA1 (0.41) | SPHK1LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432808-B1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2015-10-21 | — | — | EP | claimed |
| US-8383744-B2 | Actinically-crosslinkable siloxane-containing copolymers | NOVARTIS AG (CH) | 2013-02-26 | — | — | US | claimed |
| EP-2432808-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | Novartis AG (CH) | 2012-03-28 | — | — | EP | claimed |
| WO-2010133680-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | claimed |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | claimed |
| EP-3532519-B1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | ALCON INC (CH) | 2026-01-21 | — | — | EP | disclosed |
| EP-4263672-B1 | SELF-BLOWING ISOCYANATE-FREE POLYURETHANE FOAMS | UNIV LIEGE (BE) | 2024-10-09 | — | — | EP | disclosed |
| US-20230416487-A1 | SELF-BLOWING ISOCYANATE-FREE POLYURETHANE FOAMS | Université de Liège (BE) | 2023-12-28 | — | — | US | disclosed |
| EP-4263672-A1 | SELF-BLOWING ISOCYANATE-FREE POLYURETHANE FOAMS | Université de Liège (BE) | 2023-10-25 | — | — | EP | disclosed |
| CN-115368518-A | Colloidal particle emulsifier and preparation method and application thereof | 西南石油大学 | 2022-11-22 | — | — | CN | disclosed |
| WO-2022128822-A1 | SELF-BLOWING ISOCYANATE-FREE POLYURETHANE FOAMS | Université de Liège (BE) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015563-A1 | SELF-BLOWING ISOCYANATE-FREE POLYURETHANE FOAMS | Université de Liège (BE) | 2022-06-22 | — | — | EP | disclosed |
| US-20190229337-A1 | BLOCK GRAFT COPOLYMER BINDERS AND THEIR USE IN SILICON-CONTAINING ANODES OF LITHIUM-ION BATTERIES | UT-BATTELLE, LLC | 2019-07-25 | — | — | US | disclosed |
| WO-2018078543-A1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | NOVARTIS AG (CH) | 2018-05-03 | — | — | WO | disclosed |
| US-20180113237-A1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | ALCON INC. (CH) | 2018-04-26 | — | — | US | disclosed |
| EP-2432808-B1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2015-10-21 | — | — | EP | disclosed |
| US-20130123144-A1 | TUNABLE LCST POLYMERS AND METHODS OF PREPARATION | CORNELL UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |
| US-8383744-B2 | Actinically-crosslinkable siloxane-containing copolymers | NOVARTIS AG (CH) | 2013-02-26 | — | — | US | disclosed |
| WO-2011140409-A2 | TUNABLE LCST POLYMERS AND METHODS OF PREPARATION | CORNELL UNIVERSITY (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100296049-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | VCL, MACF1, CFL1 | SPHK1 4158/4885LMNA 1029/4885CA2 3267/4885 |
| US-20130123144-A1 | TUNABLE LCST POLYMERS AND METHODS OF PREPARATION | LCP1, DLST, ALG1 | SPHK1 3026/4885LMNA 317/4885CA2 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.