Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527336 | 0.87 | SIGMAR1 (0.51) | OPRD1OPRK1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL23540110 | 0.83 | OPRD1 (0.45) | OPRD1OPRK1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL7983083 | 0.78 | PDK1 (0.55) | OPRD1OPRK1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL7983089 | 0.78 | PDK1 (0.55) | OPRD1OPRK1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL7983086 | 0.78 | PDK1 (0.55) | OPRD1OPRK1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL17086784 | 0.78 | KMT2A (0.49) | OPRD1OPRK1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL317705 | 0.78 | ADORA3 (0.57) | OPRD1OPRK1ALDH1A1MAPK1ADORA3 | |
| SCHEMBL3151932 | 0.78 | KMT2A (0.49) | OPRD1OPRK1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL3151938 | 0.78 | KMT2A (0.49) | OPRD1OPRK1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL4832341 | 0.78 | BRD4 (0.48) | ALDH1A1TSHRS1PR5S1PR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |