Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838741 | 0.79 | PYGL (0.50) | GPR132LPAR1ERAP1CTSKCTSL | |
| SCHEMBL1836676 | 0.79 | CTSK (0.61) | GPR132CTSKCTSLCTSSCTSB | |
| SCHEMBL1837320 | 0.78 | CNR2 (0.49) | KDM4ELPAR1ERAP1CTSKCTSL | |
| SCHEMBL1837613 | 0.77 | TSHR (0.59) | MAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL1842072 | 0.77 | TSHR (0.69) | MAPTKDM4EPTGS2TSHR | |
| SCHEMBL1813782 | 0.77 | CTSL (0.64) | ERAP1CTSKCTSLCTSSCTSB | |
| SCHEMBL1839626 | 0.77 | GPR132 (0.47) | HDAC6GPR132LPAR1TSHRERAP1 | |
| SCHEMBL5105059 | 0.76 | FABP4 (0.51) | MAPTKDM4ETSHRERAP1CTSK | |
| SCHEMBL5599694 | 0.75 | DHODH (0.47) | GPR132LPAR1CTSLCTSSCTSB | |
| SCHEMBL1837480 | 0.75 | MAOA (0.49) | HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008592-B1 | Cyclic amide derivatives which inhibit cathepsin K | SEIKAGAKU KOGYO CO LTD (JP) | 2006-02-01 | — | — | EP | disclosed |