Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668034 | 0.94 | CCR3 (0.37) | MCHR1CCR3DRD2DRD4TSHR | |
| SCHEMBL8717803 | 0.93 | CCR3 (0.40) | MCHR1CCR3TSHRSLC6A12TMEM97 | |
| SCHEMBL8500944 | 0.84 | MCHR1 (0.34) | MCHR1CCR3DRD2DRD4MTTP | |
| SCHEMBL8501237 | 0.81 | MTTP (0.36) | DRD2DRD4MTTPCHRM1MEN1 | |
| SCHEMBL8665214 | 0.80 | MCHR1 (0.37) | MCHR1CCR3DRD2DRD4SLC6A12 | |
| SCHEMBL8501050 | 0.79 | MTTP (0.36) | DRD2DRD4MTTPCHRM1MEN1 | |
| SCHEMBL8480060 | 0.79 | CCR3 (0.40) | MCHR1CCR3CYP2C9SLC6A12TMEM97 | |
| SCHEMBL8665881 | 0.77 | DRD2 (0.37) | MCHR1DRD2DRD4MTTPCHRM1 | |
| SCHEMBL8666097 | 0.75 | DRD2 (0.36) | MCHR1DRD2DRD4MTTPCHRM1 | |
| SCHEMBL8668000 | 0.75 | KMT2A (0.37) | DRD2DRD4CNR2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |