Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503196 | 0.83 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL8504731 | 0.78 | HPGDS (0.35) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL8502519 | 0.74 | MRGPRX4 (0.36) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL8502116 | 0.74 | MEN1 (0.38) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL8506458 | 0.73 | MRGPRX4 (0.37) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL8502108 | 0.72 | KMT2A (0.39) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL8504856 | 0.71 | ALDH1A1 (0.47) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL8505814 | 0.71 | ADRB2 (0.42) | RAB9AMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8503702 | 0.69 | IL4I1 (0.37) | POLB | |
| SCHEMBL8501895 | 0.68 | HTT (0.40) | RAB9AMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |