Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | GIPR | P48546 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503797 | 0.92 | MAPK1 (0.44) | MAPK1MAPK10SMN1; SMN2PTGER1IDO1 | |
| SCHEMBL8505812 | 0.88 | ADRB2 (0.42) | NLRP3MAPK1KDM4EIDO1USP2 | |
| SCHEMBL8502188 | 0.85 | GAA (0.38) | MAPK1MAPK10SMN1; SMN2KDM4EPTGER1 | |
| SCHEMBL8504729 | 0.83 | IDO1 (0.41) | SMN1; SMN2KDM4EHIF1AIDO1ALDH1A1 | |
| SCHEMBL8504781 | 0.82 | MAPK1 (0.39) | MAPK1MAPK10KDM4EIDO1ALDH1A1 | |
| SCHEMBL8506457 | 0.82 | IDO1 (0.39) | MAPK1SMN1; SMN2KDM4EHIF1AIDO1 | |
| SCHEMBL8502514 | 0.81 | IDO1 (0.40) | SMN1; SMN2KDM4EHIF1APPARGIDO1 | |
| SCHEMBL8502112 | 0.81 | IDO1 (0.40) | SMN1; SMN2KDM4EHIF1AIDO1ALDH1A1 | |
| SCHEMBL8503177 | 0.81 | POLB (0.38) | MAPK1PTGER1IDO1USP2ALDH1A1 | |
| SCHEMBL8505616 | 0.74 | L3MBTL1 (0.42) | NLRP3GCGRGIPRSMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |