Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505614 | 0.92 | NLRP3 (0.41) | MAPK1MAPK10ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL8505812 | 0.90 | ADRB2 (0.42) | MAPK1ALDH1A1USP2POLBKMT2A | |
| SCHEMBL8504781 | 0.88 | MAPK1 (0.39) | MAPK1MAPK10ALDH1A1NPC1RAB9A | |
| SCHEMBL8502188 | 0.87 | GAA (0.38) | MAPK1MAPK10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8504729 | 0.85 | IDO1 (0.41) | ALDH1A1RAB9ASMN1; SMN2POLBKMT2A | |
| SCHEMBL8506457 | 0.84 | IDO1 (0.39) | MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8502112 | 0.83 | IDO1 (0.40) | ALDH1A1SMN1; SMN2POLBIDO1CYP1A2 | |
| SCHEMBL8502514 | 0.83 | IDO1 (0.40) | ALDH1A1SMN1; SMN2KMT2AIDO1TP53 | |
| SCHEMBL8503177 | 0.82 | POLB (0.38) | MAPK1ALDH1A1USP2PTGER1POLB | |
| SCHEMBL8504974 | 0.79 | ALDH1A1 (0.38) | MAPK1MAPK10ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |